William V. Curran,Christopher M. Liu,Amy C.D. Bombardier,Richard A. Leese,You Seok Hwang,Blaise S. Lippa,Yanzhi Zhang
申请号：
US13835470
公开号：
US20140073559A1
申请日:
2013.03.15
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Provided herein are novel compounds and novel protected compounds that can be derived from polymyxin, including, e.g., polymyxin A. The novel compounds have antibacterial properties against a diverse range of Gram negative bacteria and reduced toxicity compared to polymyxins such as polymyxin A. Also provided are antibacterial pharmaceutical compositions containing the novel compounds and novel protected compounds, as well as methods for preparing the antibacterial compounds and protected compounds.
