PROBLEM TO BE SOLVED: To provide compositions in which cilostazol is maintained in an amorphous state for a fixed time inside a digestive tract after oral administration, and to provide methods of producing the compositions.SOLUTION: A composition is a solid dispersion containing cilostazol represented by the formula (1), and methacrylic acid copolymer S and/or methacrylic acid copolymer L which are enteric-coated polymers, wherein cilostazol is dispersed in an amorphous state into a methacrylic acid copolymer, and their weight ratio is 1:0.5-1:3, the composition being prepared by a thermal fusion method or heating and kneading fusion method, and subsequently cooled and pulverized to be produced.SELECTED DRAWING: None【課題】シロスタゾールが経口服用後に消化管内部で一定時間非晶質状態を維持される組成物、および組成物の製造方法の提供。【解決手段】式（１）で表されるシロスタゾールと腸溶性高分子であるメタクリル酸コポリマーＳ及び／又はメタクリル酸コポリマーＬを含み、シロスタゾールがメタクリル酸コポリマー中に非晶質状態で分散されている固体分散体で、これらの重量比が１：０．５～１：３であり、熱溶融法又は加熱混練溶融法によって調製した後、冷却および粉砕して製造した固体分散体である組成物。【選択図】なし
