It is intended to induce cell death and inhibit cell growth for cancer cells.The agents of the present invention comprise, as active ingredients, a drug inhibiting GST-π and a drug inhibiting a homeostasis-related protein that exhibits synthetic lethality when inhibited together with GST-π.本發明對於癌細胞可誘導細胞死亡,且抑制細胞增殖。本發明包含抑制GST-π之藥物、與抑制若與GST-π一併被抑制則顯示出合成致死性之恆常性維持相關蛋白質的藥物作為有效成分。【本案指定代表圖】:第(12)圖。