Institut Curie;Société Splicos;Centre National De La Recherche Scientifique;Universite Montpellier 2
发明人:
Florence Mahuteau,JAMAL TAZI,Romain Najman
申请号:
BRPI1012892
公开号:
BRPI1012892A2
申请日:
2010.06.14
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The present invention relates to compound (I)wherein:R independently represents a hydrogen atom, a halogen atom or a group chosen among a -CN group, a hydroxyl group, a -COORgroup, a (C-C)fluoroalkyl group, a (C-C)fluoroalkoxy group, a -NOgroup, a -NRRgroup, a (C-C)alkoxy group, a phenoxy group and a (C-C)alkyl group; Rand Rare independently a hydrogen atom or a (C-C)alkyl group; n is 1, 2 or 3; n' is 1 or 2; R' is a hydrogen atom, a halogen atom or a group chosen among a (C-C)alkyl group, a hydroxyl group, a -COORgroup, a -NOgroup, a -NRRgroup, a morpholinyl or a morpholino group, a N-methylpiperazinyl group, a (C-C)fluoroalkyl group, a (C-C)alkoxy group and a -CN group; R" is a hydrogen atom or a (C-C)alkyl group, and Z is C, V is C, Y is C, X is C, T is N, U is C and W is C, for use as an agent for preventing, inhibiting or treating cancer.Some of said compounds are new and also form part of the invention.