CELLULE E. COLI PROBIOTIQUE TRANSGÉNIQUE

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专利权人:

Freie Universität Berlin

发明人:

申请号：

EP19163295.9

公开号：

EP3708180A1

申请日:

2019.03.15

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The invention relates to a transgenic probiotic E. coli cell genetically engineered to express and secrete a nematode-derived immunomodulator. The cell comprises chromosomal E. coli DNA, wherein the genetic information for expression and secretion of the nematode-derived immunomodulator is integrated into the chromosomal E. coli DNA and wherein the E. coli cell is an auxotrophic cell lacking genetic information necessary for synthesizing a compound required for the growth of the E. coli cell.

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