PREPARATION FOR PREVENTING OR AMELIORATING WRINKLES, TO BE TAKEN ORALLY, THROUGH INJECTION, OR THROUGH EXTERNAL APPLICATION TO SKIN, AND COSMETIC METHOD
PROBLEM TO BE SOLVED: To provide a novel heparanase activity inhibitor.SOLUTION: Provided is a heparanase activity inhibitor consisting of one or more selected from a Japanese valerian extract, Japanese cypress extract, kiwi extract, lemon extract, tomato extract, garlic extract, lily extract, Peucedanum japonicum extract, Sapindus mukurossi extract, parsley extract, jujube extract, Citrus Unshiu Peel extract and Nettle extract.【課題】新規ヘパラナーゼ活性阻害剤の提供。【解決手段】カノコソウエキス、ヒノキエキス、キウイエキス、レモンエキス、トマトエキス、ニンニクエキス、ユリエキス、長命草（ボタンボウフウ）エキス、ムクロジエキス、パセリエキス、タイソウエキス、チンピエキス、およびイラクサエキスの中から選ばれる１種または２種以上からなるヘパラナーゼ活性阻害剤の提供。【選択図】図９
