The present invention provides a novel topical moisturizing preparation containing as an active ingredient at least one selected from pentosan polysulfate； pharmaceutically acceptable salts of pentosan polysulfate； and pharmaceutically acceptable solvates thereof. The topical moisturizing preparation of the present invention, which contains a substance free of animal-derived components as an active ingredient, can be produced as a topical moisturizing preparation free of animal-derived components, as needed.
