PROBLEM TO BE SOLVED: To provide compounds which have excellent Pim inhibitory action and are useful as pharmaceuticals.SOLUTION: A compound is a thiazolidine derivative represented by the general formula (1) in the figure, or a salt thereof. (In the formula, X represents O or S R3 represents a hydrogen atom or a C1-6 alkyl group Z1, Z2, Z3, Z4, Z5 and Z6 each independently represent CH or N Y represents an optionally substituted, divalent C6-14 aromatic hydrocarbon group or the like Am represents a disubstituted amino group, or an optionally substituted, nitrogen-containing saturated heterocyclic group and R1 and R2 each independently represent a hydrogen atom, a halogen atom, an alkyl group or the like.)COPYRIGHT: (C)2015,JPO&INPIT【課題】優れたPim阻害作用を有し、医薬として有用な化合物を提供する。【解決手段】一般式(1)(式中、Xは、O又はSを示し;R3は、水素原子又はC1-6アルキル基を示し;Z1、Z2、Z3、Z4、Z5及びZ6は、それぞれ独立してCH又はNを示し;Yは、置換基を有していてもよい2価のC6-14芳香族炭化水素基等を示し;Amは、二置換アミノ基、又は置換基を有していてもよい窒素含有飽和複素環式基を示し;R1及びR2は、それぞれ独立して、水素原子、ハロゲン原子、アルキル基等を示す。)で表されるチアゾリジン誘導体又はその塩。【選択図】なし
