COMPOSITIONS ET PROCEDES DE MODULATION DE L'ACTIVITE DES CYTOKINES DE LA FAMILLE D'IL-20

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专利权人:

THE UAB RESEARCH FOUNDATION

发明人:

WALTER, MARK

申请号：

CA2878825

公开号：

CA2878825A1

申请日:

2013.07.10

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

Provided herein are compositions comprising one or more agents that inhibit or reduce the activity of IL-20. Optionally, the agents further inhibit or reduce the activity of IL-24. Kits and method of treating or preventing an inflammatory or autoimmune disease using the compositions are also provided. In addition, provided are methods of screening for agents that selectively bind the IL-20R1/IL-20R2 receptor complex or that selectively bind the IL-22R1/IL-20R2 receptor complex. The methods include contacting an agent to be screened with the receptor and determining whether the agent selectively binds to the receptor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/