您的位置: 首页 > 农业专利 > 详情页

Sensizitation of cancer cells to therapy using sina targeting genes from the 1p and 19q chromosomal regions
专利权人:
发明人:
申请号:
EP10167455.4
公开号:
EP2336320B1
申请日:
2007.07.23
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The invention relates to the identification of genes involved in resistance of cancer cells to therapy, to short nucleic acid molecules which inhibit the expression of these genes by RNA interference and to their use as adjuvant in cancer therapy, to sensitize cancer cells to conventional anticancer agents said short nucleic acid molecules are double-stranded short interfering nucleic acid molecules comprising a sense and an antisense region, wherein the sense region comprises a nucleotide sequence that is selected from the group consisting of: the sequences SEQ ID NO: 15, 11, 13, 14, 30, 31, 38, 46, 64 and 70 and the sequences having at least 70 % identity, preferably at least 80 % identity, more preferably at least 90 % identity with said sequences, and the antisense region comprises a nucleotide sequence that is complementary to the sense region.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充