Joseph E. Bugaj,Henry C. Manning,Eliot T. McKinley,Robert C. Wild
申请号:
US13576975
公开号:
US20130137975A1
申请日:
2011.02.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A method for determining whether to administer a therapeutically effective amount of a receptor tyrosine kinase-inhibiting drug for tumor treatment, by determining a glucose uptake response in the tumor of a mammal. 18FDG-PET (2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography imaging) is used as a predictive, non-invasive, pharmacodynamic biomarker of response following administration of drug.