WONG, CHI HUEY,翁启惠,翁啟惠,WU, CHUNG YI,吴宗益,吳宗益,CHEN, ALICE,陈铃津,陳鈴津,YU, JOHN,游正博,游正博
申请号:
TW102105871
公开号:
TW201328705A
申请日:
2009.08.19
申请国别(地区):
TW
年份:
2013
代理人:
摘要:
The present invention relates to an immunogenic composition comprising a glycan conjugate including a carrier protein and a glycan comprising Globo H, an immunogenic fragment thereof, or stage-specific embryonic antigen-4 (SSEA-4), wherein the glycan is conjugated with the carrier protein through a linker. The immunogenic composition of the invention is useful for treatment of cancer.本發明提供一種免疫原性組合物,其包含聚醣共軛物,該聚醣共軛物包含載體蛋白及聚醣,其中該聚醣包含Globo H,其免疫原性片段或SSEA-4,其中該聚醣係經由連接子與載體蛋白共軛連結。本發明之免疫原性組合物可用於治療癌症。