PROBLEM TO BE SOLVED: To provide a cool feeling agent, a TRPM8 activator and a method for imparting cool feeling, excellent in activation action of TRPM8 as a receptor exhibiting response to menthol and cold stimulus, and a novel compound useful for imparting cool feeling.SOLUTION: The cool feeling agent has as an effective ingredient a compound represented by formula (1) wherein R1 is a hydrogen atom R2 is a hydrogen atom, a hydroxy group or a 1-3C alkoxy group R3 is a hydrogen atom or a hydroxy group R4 is a hydrogen atom, a 1-6C alkyl group, a 2-6C alkenyl group or a 1-3C alkoxy group R5 is a hydrogen atom or a 1-3C alkoxy group and R6 is a hydrogen atom, a hydroxy group, a 1-14C alkoxy group, an alkoxyalkoxy group having 2 to 12 total carbon atoms, a 3-12C cycloalkoxy group, a 6-12C aryloxy group, an aralkyloxy group having 7 to 14 total carbon atoms, or an alkanoyloxy group having 2 to 12 total carbon atoms.COPYRIGHT: (C)2013,JPO&INPIT【課題】メントール及び冷刺激に応答性を示す受容体であるTRPM8の活性化作用に優れる冷感剤、TRPM8活性化剤及び冷感付与方法、並びに冷感付与に有用な新規化合物の提供。【解決手段】式(1)で表される化合物を有効成分とする冷感剤。【選択図】なし
