A fastener cartridge can comprise a compressible collapsible and/or crushable cartridge body and fasteners embedded within the cartridge body which can be utilized to fasten tissue. In use the fastener cartridge can be positioned in a first jaw of a surgical fastening device wherein the first jaw can be positioned opposite a second jaw or anvil. The anvil can be engaged with the fastener cartridge to compress collapse and/or crush the cartridge body and deform or otherwise deploy the fasteners contained therein. As the fasteners are deformed or deployed the fasteners can capture at least a portion of the cartridge body therein along with at least a portion of the tissue being fastened. The staple cartridge can further comprise a support retainer. The support retainer can be detachably connected to the cartridge body such that the cartridge body can be implanted and the support retainer can remain with the first jaw.