Alison ONeill,Douglas B. Jacoby,Abdellah Sentissi,Kamala Kesavan,E. Michael Egan
申请号:
US13479203
公开号:
US20130045163A1
申请日:
2012.05.23
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is directed to methods and methods for the treatment, inhibition and/or reduction, and detection of metastatic tumors. In some embodiments, the inventive methods include systemic (e.g., intravenous) administration of a chlorotoxin agent that may or may not be labeled. In some embodiments, the inventive methods allow treatment, inhibition and/or reduction, and detection of metastases in the brain. In some embodiments, neovascularization is inhibited and/or newly formed vessels are caused to regress.