Methods of expanding tumor infiltrating lymphocytes (TILs), includingperipheral blood lymphocytes and marrowinfiltrating lymphocytes, from blood and/or bone marrow of patients withhematological malignancies, such as liquid tumors, includinglymphomas and leukemias, and uses of such expanded TILs in the treatment ofdiseases such as cancers and hematological malignanciesare disclosed herein.