Duncan Scott,Zeidan Tarek A.,Thomas Wynn,Hencken Christopher P,Sanrame Carlo N
申请号：
NZ63133714
公开号：
NZ631337A
申请日:
2014.03.14
申请国别(地区):
NZ
年份:
2017
代理人:
摘要：
Disclosed are prodrugs of fumaric acid esters or fumarates of formula (III) where the variables are as disclosed in the specification. The compounds are useful in the treatment of neurological diseases such as multiple sclerosis. Examples of compounds include: 2-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)ethyl methyl fumarate 3-(2,5-Dioxopyrrolidin-1-yl)propyl methyl fumarate and 2-(1,3-Dioxoisoindolin-2-yl)ethyl methyl fumarate.
