Ramasamy M. Mannan;Richard L. Krebs;Paul J. Dominowski;Pamela K. Klose
发明人:
Paul J. Dominowski,Ramasamy M. Mannan,Richard L. Krebs,Pamela K. Klose
申请号:
US12650715
公开号:
US08771727B2
申请日:
2009.12.31
申请国别(地区):
US
年份:
2014
代理人:
摘要:
This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsically. Methods of preparing the emulsions and vaccines are also provided by the present invention.