LANDER CYNTHIA,BROPHY COLLEEN,PETERSON CARYN,LUBER ANDREW
申请号:
IN201717031812
公开号:
IN201717031812A
申请日:
2017.09.08
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The described invention provides pharmaceutical compositions systems and methods for treating a non small cell lung cancer (NSCLC) solid tumor comprising a population of tumor cells. The method includes administering a pharmaceutical composition comprising a therapeutic amount of a polypeptide having the amino acid sequence YARAAARQARAKALARQLGVAA (SEQ ID NO: 1) or functional equivalent thereof and a pharmaceutically acceptable carrier wherein therapeutic amount of the polypeptide is effective to inhibit a kinase activity in the population of tumor cells and to reduce cancer cell proliferation to reduce tumor size to reduce tumor burden to induce tumor cell death to overcome tumor chemoresistance to enhance tumor chemosensitivity or a combination thereof.