sedative or anesthetic delivery host / guest composition, anesthetic or sedative composition, anesthetic or sedation composition, method of induction or maintenance by intermittent bolus administration or infusion, anesthesia or sedation in an individual, 5 use of neuroactive steroid anesthetic and clodextrin or a modified form thereof in the manufacture of a medicament for inducing anesthesia in an individual and method of inducing or maintaining by intermittent bolus administration or infusion, sedation in a human subject.
BENJAMIN JAMES BOYD,COLIN STANLEY GOODCHILD,JULIET MARGUERITE GOODCHILD
申请号:
BR112012017800
公开号:
BR112012017800A2
申请日:
2011.01.19
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The present invention relates generally to the field of drug delivery systems for neuroactive steroid anaesthetic agents. More particularly, anaesthetic and sedative formulations are provided in the form of host/guest preparations comprising one or more neuroactive steroid anaesthetics and a cyclodextrin. Particular cyclodextrins contemplated include sulfoalkyl ether cyclodextrins and modified forms thereof.