您的位置: 首页 > 农业专利 > 详情页

Animal having modification in MGAT2 gene
专利权人:
Naomoto Harada;Yoshiki Ito;Yoshitaka Tamai;Naomi Murai;Katsumi Aragane;Yukina Tokushima;Takaharu Maruyama;Jun Kusunoki;Katsuya Ohbuchi
发明人:
Katsumi Aragane,Katsuya Ohbuchi,Yoshitaka Tamai,Naomoto Harada,Naomi Murai,Yoshiki Ito,Jun Kusunoki,Yukina Tokushima,Takaharu Maruyama
申请号:
US12525410
公开号:
US08232447B2
申请日:
2007.11.30
申请国别(地区):
US
年份:
2012
代理人:
摘要:
It is an object to provide a gene-modified non-human animal having inactivated MGAT2 gene and a gene-modified non-human animal cell, which are useful for the search of the function of MGAT2 in vivo. It is another object to provide a method for screening of a compound capable of inhibiting the activity of MGAT2 and a compound capable of inhibiting the activity of MGAT2. It is further another object to provide a method for detecting a disease induced by abnormal lipid metabolism based on the expression level or activity of MGAT2. A method for screening of a compound by using a gene-modified non-human mammal having the artificially inhibited expression of MGAT2 gene and a cell thereof enable to prevent or treat a disease induced by abnormal lipid metabolism. Also a screening of a compound capable of inhibiting or enhancing the function of MGAT2 enables to prevent or treat a disease induced by abnormal lipid metabolism.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
相关专利

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充