Laurent Magnenat,Olivier Leger,Charles MacKay,David Georges Zahra
申请号:
US13988498
公开号:
US09567398B2
申请日:
2011.11.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to antibodies with specificity for granulocyte-macrophage colony stimulating factor (GM-CSF). More particularly, the invention relates to humanized monoclonal antibodies that bind specifically to human GM-CSF with high affinity. The invention also relates to nucleic acids encoding the antibodies, vectors for expression of these nucleic acids, and host cells for producing said antibodies. Further, the invention relates to the use of said antibodies in the diagnosis or treatment of autoimmune or inflammatory diseases.