ДАМАК Сами (CH),СЕТУР-РОЗЕ Филипп (FR),ЛЁ КУТР Йоханнес (CH)
申请号：
RU2013147976/15
公开号：
RU2013147976A
申请日:
2012.03.29
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. A composition comprising at least one inhibitor Trpm5, for use in treating preventing metabolic disorders without reducing pischi.2 consumption. The composition for use according to claim 1, for use in maintenance of weight reduction and / or maintaining the mass in humans and / or zhivotnyh.3. The composition for use according to any of the preceding claims for use in the treatment of overweight or ozhireniya.4. The composition for use according to claim 1, wherein avoided "yo-yo effect" 5. The composition for use according to claim 1 for use in reducing zhira.6 mass. The composition for use according to claim 1, wherein the metabolic disorder is selected from the group consisting of diabetes, hypertension and cardiovascular zabolevaniy.7. The composition for use according to claim 1, which is selected from the group consisting of food compositions, nutritional compositions, nutraceuticals powdered nutritional products, reconstituted with water or milk before drinking, food additives, pharmaceuticals, beverages and pet zhivotnyh.8. The composition for use according to claim 1, wherein the inhibitor is quinine Trpm5 ((R) - (6-metohinolin-4-yl) ((2S, 4S, 8R) -8-vinilhinuklidin-2-yl) metanol.9 composition. for use according to claim 1, wherein the inhibitor is Trpm5 hinina.10 hydrochloride. a composition for use according to claim 1, wherein the inhibitor is quinine Trpm5 sulfat.11. The composition for use according to claim 1, comprising Trpm5 inhibitor in an amount of at least 0.1 mg / kg of the composition, at least 0.5 mg / kg of composition, or at least 1 mg / kg kompozitsii.12. The composition for use according to claim 1, which is administered I in an amount corresponding to at least 0.003 mg yn powdered nutritional products, reconstituted with water or milk before drinking, food additives, pharmaceuticals, beverages and pet zhivotnyh.8. The composition for use according to claim 1, wherein the inhibitor is quinine Trpm5 ((R) - (6-metohinolin-4-yl) ((2S, 4S,
