IMPROVED FORMULATIONS OF AMINOGLYCOSIDE AND FOSFOMYCIN COMBINATIONS AND METHODS AND SYSTEMS FOR TREATMENT OF VENTILATOR ASSOCIATED PNEUMONIA (VAP) AND VENTILATOR ASSOCIATED TRACHEAL (VAT) BRONCHITIS
The present invention is antibiotic compositions, ventilator based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an in-line nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.本發明係一種與呼吸器相關性肺炎(VAP)及呼吸器相關性氣管(VAT)支氣管炎相關之抗生素組合物、基於呼吸器之系統及方法。經由該呼吸器之氣道內之線上型噴霧器投與磷黴素及胺基糖苷(較佳係阿米卡星(amikacin))之抗生素組合。增濕條件會產生治療VAP及VAT之改良氣霧劑氣霧。1‧‧‧呼吸器2‧‧‧吸氣支路3‧‧‧呼氣支路4‧‧‧增濕器5‧‧‧線上型噴霧器6‧‧‧固定件
