Insulated antiviral link proteins that link IL-23 include at least one variable region of heavy and light chains, including variant CDRS; nucleic acid, vector and Hospedera coding; pharmacological synthesis; and use in the treatment of related diseases. Isaac calls a patient
TOWNE, JENNIFER E.,CHENG, JANET D.,O'NEILL, JASON C.,ZHANG, YU,SUN, YU,CERNE, HEATHER,PIPER, DEREK E.,KETCHEM, RANDAL R.
申请号:
CL2012001096
公开号:
CL2012001096A1
申请日:
2012.04.26
申请国别(地区):
CL
年份:
2012
代理人:
摘要:
Protein Binding to Antigen isolated from il-23, which comprises at least a variable region of heavy chain and light chain comprising mutated CDRs; Nucleic AcidVector and host cell that encode; Pharmaceutical Composition and its use for treating Diseases associated with IL - 23 in a patient.<;p>;Proteí;na de enlace a antí;geno aislada que enlaza IL-23, que comprende al menos tanto una regió;n variable de cadena pesada como de cadena liviana que comprenden CDRS mutadas; á;cido nucleico, vector y cé;lula hospedera que la codifican; composició;n farmacé;utica; y su uso para tratar enfermedades asociadas a IL-23 en un paciente.<;/p>;