The present invention relates to a drug delivery system suitable for mucosal delivery comprising solid lipid nanoparticles (SLNs) wherein the solid lipid nanoparticles comprise of a drug-cyclodextrin inclusion complex, one or more of polymer(s), lipid(s), surfactant(s), co-surfactant(s) and cryoprotector(s) along with one or more pharmaceutically acceptable excipients. The present invention also relates to a pharmaceutical composition comprising this delivery system and a process for the preparation of such composition thereof.