BOLSHAKOVA, ANASTASIYA YEVGENYEVNA,BORISHPOLSKIY, ANDREY LEONIDOVICH,KNYAZKIN, GENNADY JURIEVICH,MELNIKOVA, NINA BORISOVNA,POLUKHIN, IGOR VALENTINOVICH,POLUKHIN, OLEG VALENTINOVICH,PYANZINA, IRINA PET
申请号：
EP11849265
公开号：
EP2656852A4
申请日:
2011.11.22
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The invention relates to the field of medicine and pharmaceutics and, more specifically, to the creation of a pharmaceutical composition in the form of a suspension for the prevention and treatment of disorders in the physiological and reparative regeneration of tissues of the musculoskeletal system, i.e. osseous tissue and articular cartilage. The pharmaceutical compositions stimulating the regeneration of the osseous tissue and articular cartilage comprise the substance "Micellate of calcium and magnesium carbonates". The conducted trials have shown that the proposed pharmaceutical compositions have an apparent specific pharmacological activity, exhibiting a reparative and regenerative effect with respect to bone tissue in animals, and do not have a marked general toxic effect in different doses and routes of administration to laboratory animals. The compositions do not exhibit an irritant effect, and no sensitizing effect has been observed. The proposed pharmaceutical compositions are effective and safe and can be used to prevent and treat disorders in the physiological and reparative regeneration of tissues of the musculoskeletal system, inter alia in diabetes mellitus patients.
