KARL WELZENBACH,MARIANNE RAYMOND,MARIE SARFATI,MAXIMILIAN WOISETSCHLAEGER
申请号:
BRPI0923442
公开号:
BRPI0923442A2
申请日:
2009.12.17
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention relates to soluble CD47 binding polypeptides, for use as a medicament, in particular for the prevention or treatment of autoimmune and inflammatory disorders, for example allergic asthma and inflammatory bowel diseases. The invention more specifically relates to a soluble CD47 binding polypeptide for use as a medicament, comprising an extracellular domain of SIRPα (CD172a) or functional derivatives which bind to human CD47.