Specific Bacterial Species and Metabolite That Improves Immune Checkpoint Inhibitor Therapy Efficacy

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专利权人:

BOARD OF REGENTS; THE UNIVERSITY OF TEXAS SYSTEM

发明人:

Arthur E. Frankel,Andrew Y. Koh

申请号：

US16617704

公开号：

US20200129570A1

申请日:

2018.06.01

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention includes compositions and methods for increasing an efficacy of an immune checkpoint inhibitor comprising: identifying a human patient in need of treatment for a melanoma； providing the human patient with an effective amount of the immune checkpoint inhibitor； and providing the human patient with at least one of: a probiotic bacteria, a prebiotic agent, or a xenobiotic agent, in the amount is effective to increase the potency of the immune checkpoint inhibitor against the melanoma.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/