<；p>；The present invention provides a stable lyophilized composition comprising 5-Azacytidine Form I, and process for preparing thereof. The present invention provides a stable lyophilized composition comprising 5-Azacytidine Form I, and the methods of using a stable lyophilized composition comprising Crystalline 5-Azacytidine Form I for parenteral administration, provided herein to treat diseases or disorders including, e.g., cancer, disorders related to abnormal cell proliferation, hematologic disorders, or immune disorders, among others. In certain embodiments, the pharmaceutical compositions of 5-azacytidine which are parenterally administered to subjects in need thereof to treat a cancer or a hematological disorder, such as, for example, Myelodysplastic syndromes (MDS), acute myelogenous leukemia (AML).<；/p>；
