Compounds binding to the bacterial beta ring

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专利权人:

Dominique Burnouf

发明人:

Dominique Burnouf,Annick Stote,Gilles Guichard,Jérôme Wagner,Vincent Olieric

申请号：

US14111854

公开号：

US09133240B2

申请日:

2012.04.13

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to compounds which bind to the hydrophobic pocket of the β clamp, i.e., to the surface of the β ring with which said protein interacts with other proteins of the bacterial replication complex during DNA replication. These compounds are derived from the acetylated peptide AcQLDLF (P6) to improve their affinity to their target.

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