PUTNAM, DAVID,TAN, MINGCHEE,SAMAROO, KIRK J.,BONASSAR, LAWRENCE J.
申请号：
EP13846337
公开号：
EP2908861A4
申请日:
2013.10.18
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
This invention relates to methods of lubrication for biological tissue, especially joint and cartilage surfaces, and to methods of treating osteoarthritis using high molecular weight, hydrophilic polymer brushes, which mimic the structure and activity of lubricin. These synthetic lubricin analog polymer brushes (termed herein graft brush polymers), include poly(acrylic acid) backbones grafted with polyethylene glycol.
