PROBLEM TO BE SOLVED: To provide a solid agent for sodium bicarbonate dialysis having uniform contents of each of electrolyte compounds, comprising potassium chloride, calcium chloride, magnesium chloride and sodium acetate, coated on sodium chloride particles, having no problem of pulverization caused by separation of covering layers by abrasion during production, preservation and transportation and having little scattering of fine particles during preparation of dialyzate.SOLUTION: The solid agent for sodium bicarbonate dialysis in which surfaces of the sodium chloride particles are uniformly covered with microparticles of a mixture comprising potassium chloride, calcium chloride, magnesium chloride and sodium acetate is prepared by spraying an aqueous solution of the mixture comprising potassium chloride, calcium chloride, magnesium chloride and sodium acetate onto rolled, agitated and fluidized sodium chloride particles in a rolling agitating fluidized bed granulator.COPYRIGHT: (C)2010,JPO&INPIT【課題】塩化ナトリウム粒子の表面にコーティングされた塩化カリウム、塩化カルシウム、塩化マグネシウム及び酢酸ナトリウムの各電解質化合物の含量が均一である、製造時・貯蔵時・輸送時において摩耗により被覆層が剥離して粉化するおそれが少なく、透析調製時に微粉の飛散が少ない固形重曹透析用剤の提供。【解決手段】転動撹拌流動層造粒装置内で転動流動中の塩化ナトリウム粒子に、塩化カリウム、塩化カルシウム、塩化マグネシウム及び酢酸ナトリウムを含有する混合物の水溶液を噴霧して得られる、塩化ナトリウム粒子の表面が塩化カリウム、塩化カルシウム、塩化マグネシウム及び酢酸ナトリウムを含有する混合物の微粒子で均一に覆われてなる固形重曹透析用剤。【選択図】なし
