The present invention provides a composition for use in the treatment of brain injury and cerebral stoke patients. The composition comprising an effective amount of Astragalusmembranaceus extract and pharmaceutically acceptable carrier, excipients or salts. The brain injury includes the traumatic brain injury (TBI) and the acquired brain injury (ABI). The cerebral stoke includes the cerebral ischemia stroke and the cerebral hemorrhage stroke.本發明提供了治療腦損傷和腦中風患者用途的組合物,該組合物包括有效劑量的黃耆萃取物和藥學可接受的載體,賦形劑或鹽,該腦損傷包括創傷性腦損傷(TBI)和後天性腦損傷(ABI)。腦中風包括腦缺血性腦中風和出血性腦中風。