Philip Yan;Lori K. Taylor;Rebecca S. Hoffman;George R. Granneman;Elliot K. Chartash
发明人:
Rebecca S. Hoffman,Elliot K. Chartash,Lori K. Taylor,George R. Granneman,Philip Yan
申请号:
US11104117
公开号:
US08889136B2
申请日:
2005.04.11
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Multiple-variable dose methods for treating TNFα-related disorders, including Crohn's disease and psoriasis, comprising administering TNFα inhibitors, including TNFα antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.