Method for preparing 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]-benzoic acid

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专利权人:

Martin Grepl;Radek Melnicky;Lubomir Kvapil;Petr Slezar;Pavel Hradil

发明人:

Radek Melnicky,Pavel Hradil,Lubomir Kvapil,Martin Grepl,Petr Slezar

申请号：

US12864907

公开号：

US08129421B2

申请日:

2008.06.16

申请国别(地区):

US

年份:

2012

代理人:

摘要：

A method for preparing 4-[3,5-bis(2-hydroxyphenyl )-[1,2,4]triazol-1-yl]benzoic acid of formula (I) by reaction of 2-(2-hydroxyphenyl)benz[e][1,3]oxazin-4-one of formula (II) with 4-hydrazinobenzoic acid of formula (III) in an organic acid or in a mixture of an organic acid and an organic solvent.

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