A method for assessing suture line integrity includes loading a navigation plan into a navigation system, the navigation plan including a planned pathway shown in a 3D model, inserting a probe into a patient's airways, the probe including a location sensor in operative communication with the navigation system, registering a sensed location of the probe with the planned pathway, and selecting a target in the navigation plan, the target including a proposed suture line. The method further includes presenting a view of the 3D model showing the planned pathway and indicating the sensed location of the probe, navigating the probe through the airways of the patient's lungs toward the target, and imaging the proposed suture line of the target, via the probe, to determine tissue integrity surrounding the proposed suture line.