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Apparatus for Minimizing Sample Damage During the Ablation of Biological Tissue Using a Focused Ultrashort Pulsed Laser Beam Wherein the Slope of Fluence Breakdown is a Function of the Pulse Width
专利权人:
International Business Machines Corporation
发明人:
Richard Alan Haight,Peter P. Longo,Daniel P. Morris,Alfred Wagner
申请号:
US13735394
公开号:
US20130211388A1
申请日:
2013.01.07
申请国别(地区):
US
年份:
2013
代理人:
摘要:
An apparatus for laser induced breakdown of a tissue. The apparatus has a source of a beam of one or more laser pulses in which each pulse has a pulse width equal to or less than a pulse width value corresponding to a change in slope of a curve of fluence breakdown threshold (Fth) as a function of laser pulse width (T), the change occurring at a point between first and second portions of the curve, the first portion spanning a range of relatively long pulse width where Fth varies with the square root of pulse width (T1/2) and the second portion spanning a range of short pulse width relative to the first portion with Fth versus T slope which differs from that of the first portion and an optical system focusing the one or more pulses of the beam to a point above the surface of the tissue to cause laser induced break down of the tissue.
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