Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carbox-amide and the purification thereof for use as an active pharmaceutical ingredient

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专利权人:

Bayer Pharma Aktiengesellschaft

发明人:

Platzek, Johannes,Garke, Gunnar,Grunenberg, Alfons

申请号：

AU2015295376

公开号：

AU2015295376B2

申请日:

2015.07.29

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

The invention relates to a new and improved method for preparing (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carbox-amide of formula (I) and to the production and use of the crystalline modification I of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carbox-amide of formula (I).

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