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Primer, tenyésztett adipociták génterápiára
专利权人:
Eisai R&D Management Co.; Ltd.
发明人:
Ito, Masashi,SAITO, Yasushi
申请号:
HUE10161291
公开号:
HUE025872T2
申请日:
2003.06.18
申请国别(地区):
HU
年份:
2016
代理人:
摘要:
The present invention relates to primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells. This invention provides cells suitable for gene therapy, which can replace bone marrow cells and liver cells used for conventional ex vivo gene therapy. The present invention established methods for transferring foreign genes into primary cultured adipocytes, which are suitable for ex vivo gene therapy; can be easily collected and implanted; and can be removed after implantation. Specifically, the present invention established these methods that use retroviral vectors. The present invention also established primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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