STEINER, DANIEL,BINZ, HANS KASPAR,GULOTTI-GEORGIEVA, MAYA,MERZ, FRIEDER W.,PHILLIPS, DOUGLAS,SONDEREGGER, IVO
申请号:
PL11788815
公开号:
PL2643349T3
申请日:
2011.11.25
申请国别(地区):
PL
年份:
2020
代理人:
摘要:
New designed repeat proteins with binding specificity for serum albumin are described, as well as nucleic acids encoding such serum albumin binding proteins, pharmaceutical compositions comprising such proteins, the use of such proteins to modify the pharmacokinetics of therapeutic relevant polypeptides and the use of such proteins in the treatment of diseases. The repeat proteins of the invention have a substantially increased half-life in plasma compared to proteins not binding serum albumin.