RG-cysteic acid peptide, or a compound or pharmaceutical comprising the peptide

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专利权人:

アレグロ ファーマシューティカルズ インコーポレイテッド

发明人:

マッケル、マイケル ジョン,パーク、ジョン

申请号：

JP2015096616

公开号：

JP5912201B2

申请日:

2015.05.11

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

Compounds comprising R-G-Cysteic Acid (i.e., R-G-NH-CH(CH2- SO3H)COOH or Arg-Gly-NH-CH(CH2-SO3H)COOH) and derivatives thereof, including pharmaceutically acceptable salts, hydrates, stereoisomers, multimers, cyclic forms, linear forms, drug-conjugates, pro-drugs and their derivatives. Also disclosed are methods for making and using such compounds including methods for inhibiting cellular adhesion to RGD binding sites or delivering other diagnostic or therapeutic agents to RGD binding sites in human or animal subjects.

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