Kondenzirani pirimidin-dionski derivati kot TRPA 1 modulatorji

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专利权人:

GLENMARK PHARMACEUTICALS S.A.

发明人:

CHAUDHARI SACHIN SUNDARLAL,KUMAR SUKEERTHI,THOMAS ABRAHAM,PATIL NISHA PARAG,KADAM ASHOK BHAUSAHEB,DESHMUKH VISHAL GOVINDRAO,DHONE SACHIN VASANTRAO,CHIKHALE RAJENDRA PRAKASH,KHAIRATKAR-JOSHI NEELIMA,MU,CHAUDHARI Sachin Sundarlal,KUMAR Sukeerthi,THOMAS Abraham,PATIL Nisha Parag,KADAM Ashok Bhausaheb,DESH

申请号：

SI201030523

公开号：

SI2411393T1

申请日:

2010.03.17

申请国别(地区):

SI

年份:

2014

代理人:

摘要：

The present invention relates to a process for preparing a compound of formula (Id-1) or a pharmaceutically acceptable salt thereof, which comprises reacting a compound of formula (35) with amine compound of formula (18) wherein, R 1 and R 2 , which may be same or different, are independently selected from hydrogen and substituted or unsubstituted alkyl； U is substituted or unsubstituted heterocycles selected from thiazole and isoxazole； and V is substituted or unsubstituted aryl.

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