NG, SIEW CHIEN,黄 秀娟,黃 秀娟,CHAN, KA LEUNG FRANCIS,陈 家亮,陳 家亮
申请号:
TW108148047
公开号:
TW202031277A
申请日:
2019.12.27
申请国别(地区):
TW
年份:
2020
代理人:
摘要:
The present invention resides in the discovery that certain microorganism species in the gut and feces of fecal microbiota transplantation (FMT) donors can affect the outcome of FMT treatment. Thus, novel methods are provided for identifying subjects as suitable donor to optimize FMT outcome and for pre-treating donors and/or receipients for optimized FMT outcome. Also provided are kits and compositions for improving FMT outcome, including for specific purposes such as for weight loss or cholesterol reduction.本發明依賴於以下發現,即糞便微生物群移植(FMT)供體的腸和糞便中的某些微生物能夠影響FMT治療的結果。因此,提供了用於鑒定對象為合適的供體以優化FMT結果,以及為優化的FMT結果而預處理供體和/或受體的新的方法。還提供了用於改善FMT結果,包括用於具體目的,如用於體重減輕或膽固醇降低的試劑盒和組合物。