降低由PD-L1诱导的免疫耐受性
- 专利权人:
- 上海斯丹赛生物技术有限公司
- 发明人:
- 吴昭
- 申请号:
- CN201680002926.1
- 公开号:
- CN107073138B
- 申请日:
- 2016.03.01
- 申请国别(地区):
- 中国
- 年份:
- 2018
- 代理人:
- 许天易`徐小琴
- 摘要:
- 本公开涉及用于降低与CAR T细胞疗法相关的免疫耐受性的组合物和方法。本公开的实施例包括分离的核酸序列,所述分离的核酸序列包含编码经修饰的程序性细胞死亡蛋白质1(PD‑1)的核酸序列和编码嵌合抗原受体(CAR)的核酸序列。
- 来源网站:
- 中国工程科技知识中心
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