A bone graft composition is described, with one or more of: (a) keratose； (b) kerateine； (c) optionally, particulate filler； (d) optionally, an antibiotic； and (e) water or saline. The composition may be provided in sterile form in a container, and optionally lyophilized. Methods of treating a bone deficiency or fracture making use of such compositions are also described.
