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DÉRIVÉ DE PYRIMIDINE-2,4-DIAMINE ET COMPOSITION PHARMACEUTIQUE ANTICANCÉREUSE EN CONTENANT EN TANT QUE PRINCIPE ACTIF
专利权人:
Korea Research Institute of Chemical Technology
发明人:
申请号:
EP15809090.2
公开号:
EP3159338A2
申请日:
2015.05.21
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention relates to a pyrimidine-2,4-diamine derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for prevention or treatment of cancer comprising the same as an effective ingredient. A compound according to the present invention has the good effect of inhibiting anaplastic lymphoma kinase (ALK) activity, whereby a therapeutic effect on cancer cells having an anaplastic lymphoma kinase (ALK) fusion protein such as EML4-ALK, NPM-ALK, etc. can be enhanced and it is expected that a recurrence of cancer will be effectively inhibited. As such, the compound can be effectively used in a pharmaceutical composition for prevention or treatment of cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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