Young Kee SHIN,Young Deug Kim,Jun Young Choi,Tae Eun Kim,Young Jin Lee,Jun Ho Lee,Yeong Mun Kim
申请号：
US15693148
公开号：
US20180236092A1
申请日:
2017.08.31
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to an immunocytokine in which a human interferon-beta variant is conjugated to an antibody or a fragment thereof, and a method for preparing the same. The human interferon-beta variant has superior activity or functions compared with natural interferon-beta, and the productivity of the immunocytokine according to the present invention is excellent. In addition, the immunocytokine according to the present invention can be favorably used as a target therapeutic agent for multiple sclerosis or cancer since the immunocytokine express both of functions of the interferon-beta and characteristics of the antibody binding to a specific antigen.
