The present invention concerns hygiene tissue (1), such as a wet wipe, dry wipe, washcloth, patch, towelette, napkin, and the like comprising a microbe-inhibiting composition (8), said microbe-inhibiting composition (8) comprising an extracellular product of at least one probiotic bacterium and at least one additive in the form of an organic acid, with at least one of its pKa value not exceeding 5.5, and/or a salt thereof.