A guidewire capable of suppressing an increase in operating resistance during pushing and pulling within a blood vessel that is extremely crooked and securing sufficient operability is provided. A guidewire (10) includes a core shaft (20) and a coil body (30) wound around the core shaft (20). The core shaft (20) includes a first shaft portion (22) positioned on an inner side of the coil body (30) and a second shaft portion (24) positioned on a base end side of the coil body (30), and a twisted portion (26) that is twisted along a longitudinal direction (N) is provided in at least a portion of the second shaft portion (24).